The team currently comprises seven permanent scientists and a total of around 30 people. Our research project, which includes fundamental and translational aspects, is organized around 3 major axes:
1. Functions of selected regulatory molecules in immune responses and IMIDs
a. TMEM176b/TORID. PI: MC Cuturi and C Louvet
b. CLEC-1. PI: E Chiffoleau
c. IL-22 binding protein (IL-22BP). PI: R Josien
2. Regulatory antigen presenting cells and cell therapies.
a. Tolerogenic dendritic cells. PI: MC Cuturi and A Moreau
b. Regulatory B cells. PI: E Chiffoleau
3. Dendritic cells and immune responses to transplant-related viruses
a. Interaction with and sensing of hCMV/BKPyV by DCs: PI: F Halary and C Bressollette
b. Immune responses to BKPyV/HHV6 in transplanted patients. PI: C Bressollette and BM Imbert
Translational projects, access to human samples and clinical developments are promoted by internal and external interactions between basic researchers and clinicians and the association of a Clinical Immunomonitoring Platform (CIMNA) to the team.
Credit. Designed by Jcomp / Freepik